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Brain with dollar sign tucked into one of its folds

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NIH launches the next stage of its ‘human genome project’ for the brain

Sep 22, 2022

The National Institutes of Health on Thursday announced more than $600 million in fresh funding for an expansive and ongoing push to unravel the...

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UW Medicine pathologist C. Dirk Keene, M.D., points out large grooves in the surface of a brain of someone who died from Alzheimer's disease and donated their brain to research. In a healthy brain, these folds would nestle right up against each other but in Alzheimer's, neuron death leads to noticeable shrinkage in many parts of the brain. Keene is part of a collaborative effort to find the cellular roots of Alzheimer's. Photo by Erik Dinnel / Allen Institute

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Ask Us Anything: Alzheimer’s Disease Brain Cell Atlas

Sep 1, 2022

Scientists from the Allen Institute and UW Medicine opened up about the Seattle Alzheimer’s Disease Brain Cell Atlas on Reddit

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Keene points out brain slices from an 83-year old man who had died of Alzheimer's disease and donated his brain to research. The slices are preserved so that scientists can study how brain structures have changed in the disease. Photo by Erik Dinnel / Allen Institute

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In search of Alzheimer’s drug targets, Allen Institute builds massive brain cell map

Aug 2, 2022

The initiative, called the Seattle Alzheimer’s Disease Brain Cell Atlas (SEA-AD), has released some of its first findings at the Alzheimer’s...

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Finger points to various brain images on a computer screen

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Alzheimer’s researchers are looking beyond plaques and tangles for new treatments

Aug 1, 2022

Scientists say research into Alzheimer's needs to take a broader view of how the disease affects the brain — whether that's changes in the cortex or...

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Artistic rendering of human brain in skull and DNA strand

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Data Trove Released by Seattle Alzheimer’s Disease Brain Cell Atlas

Jul 28, 2022

Neuroscientists at the Allen Institute for Brain Science and their collaborators have released their first research data set on Alzheimer’s disease,...

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CBC Host Duncan McCue

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CBC: The Current for June 22, 2022

Jun 22, 2022

Claims that Google chat bot is sentient prompt wider questions, say experts; Russia’s invasion of Ukraine reaches four-month mark, with no end in...

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Allen Integrated Human Stem Cell Image

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It’s time to incorporate diversity into our basic science and disease models

Nov 29, 2021

Nature Cell Biology - It’s time to incorporate diversity into our basic science and disease models. Leaders in cell biology share their perspectives...

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Image of a glowing mouse brain

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Allen Institute launches new division to study brain circuits and behavior in mammals

Nov 4, 2021

GeekWire - Seattle’s Allen Institute has launched a new division called The Allen Institute for Neural Dynamics

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A new study from the Allen Institute compares human brain cells’ molecular features to those of the marmoset monkey and mouse in a region of the brain that controls movement, the primary motor cortex. Using a technique known as single-cell transcriptomics, the researchers compared the suite of genes each individual brain cell switches on, across thousands of cells from each of the three species. Shown here, transcriptomic data clustered by type of brain cell, in the human (left), marmoset monkey (middle), and mouse brain (right)

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New brain maps could help the search for Alzheimer’s treatments

Oct 6, 2021

NPR - An international consortium involving hundreds of scientists has unveiled highly detailed maps of the brain area that controls movement.

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Researcher seated at a table analyzing data on a laptop

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Share methods through visual and digital protocols

Jul 21, 2021

Nature - Documenting experimental methods ensures reproducibility and accountability, and there are innovative ways to disseminate and update them.

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Science Programs at Allen Institute