In this workshop, attendees will work in groups on a project involving data from the Seattle Alzheimer’s Disease Brain Cell Atlas (SEA-AD). The SEA-AD consortium uses single-cell molecular profiling (snRNAseq, multiome, and ATACseq), spatial transcriptomics, and quantitative neuropathology to characterize brain cell types across disease progression. The data types and brain regions currently included in the SEA-AD consortium are featured in the diagram below (SNP chip and whole genome data are restricted access and will not be used in the workshop).

resources/

• Access all SEA-AD data files here
• Explore SEA-AD data through interactive online browsers/tools here
• Programmatically access snRNAseq data from the multi-regional and caudate projects here
• Read core SEA-AD papers and related studies here

workshop highlights/

Learn how to leverage the power of cell types in your research:

• Allen Institute single nucleus- and spatial transcriptomic datasets
• Form collaborations to ideate, develop tools or models, and solve problems
• Receive guidance on projects from Allen Institute scientists
• Visit the Institute and learn about the laboratory techniques behind the datasets
• Provide user feedback to Allen Institute scientists about existing tools and documentation

As part of the application process, applicants will be asked to propose an idea involving SEA-AD datasets for the workshop. Attendees can choose to work with any single dataset, with multiple datasets, or can choose to connect one of these datasets to an externally existing dataset (not part of the SEA-AD collection) as part of their project.

Once at the workshop, groups will work on a singular project— these group projects can be one of the proposed projects, a combination of proposed projects, or something completely new. Projects can range from data analysis, to model and/or tool development, or to something else entirely. The goals of this workshop are to foster collaboration and creativity among the participants.

After the conclusion of the workshop, participants are encouraged to continue working on their projects with their group members and write-up their results however they feel appropriate. In addition, some of the Allen Institute scientists from the workshop can continue to provide as needed guidance on projects.

eligibility/

This workshop is restricted to applicants at U.S. institutions; we cannot accommodate international flights or visa sponsorship. In addition, this workshop is fully-funded and we are unable to accept self-funded applicants, institutional sponsorships, or corporate-funded attendees.

cost/

Flight & hotel will be covered*, along with breakfast & lunch during the workshop duration, and dinner the first night of the workshop. There is no application fee.

*Flight & hotel cannot exceed $2000 USD.

Applications will open on November 6, 2026 and close on January 4, 2027 at 11:59 pm PST. Applicants will be notified on February 1, 2027 of their acceptance status.

Questions? Email spoctt@alleninstitute.org