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In this lesson, students will learn how scientists at the Allen Institute are using the multimodal Patch Seq technique to define brain cell types. They will explore how neuron morphology varies among different transcriptomically defined cell types in the mouse visual cortex using the Allen Institute’s Mouse Patch Seq open dataset.
learning outcomes/
- Explain what brain cell types are and why they are important
- Describe different ways that cell types can be defined
- Evaluate the usefulness of multimodal data to define cell types
- Compare and contrast the morphology of inhibitory neurons across layers of visualcortex and transcriptomic types
Terms of use: This work is licensed under the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0). To view a copy of this license, visit https://creativecommons.org/licenses/by-nc-sa/4.0/.
Note: this resource was originally published in 2021. It's original contributors include Lauren Alfiler, Kaitlyn Casimo, Clare Gamlin, and Staci Sorensen.






