Solving the mysteries of bioscience
Foundational Science Fuels Breakthroughs
Inspiring Next-Generation Scientists
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Targeting diverse bioscience frontiers
Co-created research initiatives
The Frontiers Group participates in select collaborations with other philanthropic or funding organizations to further our impact on scientific and biomedical research. These partnerships help us make new connections in the research world, often bringing together historically disconnected fields of research. These impactful research initiatives are co-created with our partners and target diverse bioscience frontiers.
U.S. National Science Foundation – Microorganism-mediated Organismal Resilience to Climate Change
2024 – Present
In partnership with the U.S. National Science Foundation (NSF) Directorate for Biological Sciences (BIO), the Frontiers Group seeks to address significant knowledge gaps in our understanding of the molecular drivers and dynamics of microorganism resilience to climate change.
Through the NSF’s established solicitation for proposals for mechanistic studies of organismal response to climate change (ORCC), with The Paul G. Allen Family Foundation have committed to a $10 million total investment for microorganism focused research in relation to climate change in 2025.
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Research Corporation for Science Advancement and The Kavli Foundation – Scialog: Neurobiology in a Changing Ecosystems
Active 2024 – Present
Together with the Research Corporation for Science Advancement and The Kavli Foundation, the Frontiers group is supporting cutting-edge science focused on uncovering the chemical, physical, and biological principles that will aid our understanding of these complex processes, and potentially reveal what adaptive features equip organisms to overcome environmental stressors with a $1.5 million contribution.
The Scialog® funds research and facilitates intensive dialogue and community building through focused meetings. This series of meetings will connect scientists from multidisciplinary backgrounds, including genetics, neurophysiology, climate science, environmental chemistry and physical modeling to explore these existential questions and initiate new collaborations. It will bring together early-career researchers in fields that don’t commonly interact, where participants could forge new paths by investigating this emerging scientific area collaboratively.
American Heart Association – Allen Initiative in Brain Health and Cognitive Impairment
2018 – Present
As people live longer in many parts of the world, Alzheimer’s and other age-related dementias are on the rise, projected to reach more than 75 million people worldwide by 2030. Together with the American Heart Association, the Frontiers Group and the Paul G. Allen Family Foundation supports three large-scale, multidisciplinary research teams who are merging research of the brain and the blood vessels to develop a new understanding of — and ultimately better preventions and treatments for — age-related brain disorders such as Alzheimer’s disease
Through the American Heart Association-Allen Initiative in Brain Health and Cognitive Impairment, launched in 2018, the American Heart Association and The Paul G. Allen Family Foundation have committed $43 million to fund innovative approaches in combating age-related cognitive decline.
Research Team Leaders:
Blood Cancer Discoveries
Active 2019 – 2024
The Blood Cancer Discoveries Grants program is a collaboration, launched in 2019, between The Paul G. Allen Frontiers Group, The Leukemia & Lymphoma Society, and The Mark Foundation for Cancer Research. This program has identified and provided more than $6.75 million in funding to frontier scientists with deep experience in blood cancers to conduct critical basic research on leukemia, lymphoma, myeloma, and myelodysplastic syndromes.
Blood Cancer Discoveries Grant Program Recipients:
American Heart Association – Allen Distinguished Investigators
Active 2017 – 2021
In 2017, the American Heart Association partnered with The Paul G. Allen Frontiers Group and the Paul G. Allen Family Foundation to award two Allen Distinguished Investigator awards of $1.5 million, for a total of $3 million for studies of the extracellular matrix, the proteins and molecules that make up a “living glue” surrounding our cells, as it relates to the human heart and heart disease.
Lead Investigators:
