A message from our CEO
President and CEO, Rui Costa, D.V.M., Ph.D., reflects on a transformative year for the Allen Institute
From unveiling the Human Immune Health Atlas to new findings related to Alzheimer’s disease, our commitment to open science and collaboration has driven advancements in understanding life and advancing health.
A decade of cell discovery
For over 10 years, our Cell Science team has been a leader in accelerating advancements in cell biology. By creating groundbreaking tools, resources, and open-access models and datasets, we have empowered researchers and educators to explore and understand cells in new ways.

Research support for a common genetic heart condition
Our Cell Science team launched six new cell line collections to accelerate research into hypertrophic cardiomyopathy, the most common genetic heart condition. Providing researchers with these robust tools paves the way for the discovery of new treatments and insights into disease progression.
Addressing critical gaps in biomedical research
In partnership with the New York Stem Cell Foundation, researchers at the Allen Institute for Cell Science are developing ethnically diverse stem cell lines to advance equitable health research. The project aims to provide researchers with deeper insights into cellular biology that are inclusive and relevant to specific diseases.

Mapping brain cells
Unprecedented insight into immune cell aging
Our Immunology team released the Human Immune Health Atlas, a comprehensive single-cell dataset mapping healthy human immune cells from childhood to adulthood. The full dataset and interactive visualization tools are available online, providing scientists worldwide with a valuable resource to study the immune system’s evolution with age and discover new strategies to combat immune-related diseases.
Exploring how the brain learns
Each neuron in the brain functions like a tiny computer, processing inputs from thousands of synapses with millisecond precision. To understand these computations, our Neural Dynamics team developed the SLAP2 microscope.
The SLAP2 microscope
This cutting-edge tool records signals at tiny synapses in the living brain at unprecedented speed and scale. The SLAP2 steers laser light faster and more flexibly than previous microscopes. Our scientists are using this breakthrough technology to investigate how the brain learns.
Consciousness in the mammalian brain

Chronicling cellular histories


Neurobiology in changing environments
Education Program
Extending our impact
The Education & Engagement Program leverages our open science resources and cutting-edge research to engage with educational, scientific, and public communities, fostering their development in science. We seek to empower individuals at any stage of their education or career to use open science.
Through our Teacher Academy, we host educators from across the country, providing them with the opportunity to interact with our open science resources and staff. These educators learn how to incorporate these resources into their curricula, enabling them to bring open science education back to their communities. By doing so, empower these educators to inspire the next generation of scientists.
We also organize many field trips, welcoming groups of high school and undergraduate students, as well as other community groups. These visits allow students to experience our cutting-edge research firsthand, further extending our impact on future generations.
Lake Conferences
Showcasing global explorations and discoveries in Comparative and Evolutionary Neurobiology and The Neurobiology of Mental Health
Once again, the scientific community converged along the shores of Lake Washington at the 2024 Lake Conference. The conference provided an intimate setting for speakers to present and engage in impactful discussions on cutting-edge science with the potential to advance human health. Highlights included finding new approaches for studying human brain evolution and comparative brain cell atlasing, to understand brain structure and function.
Global Partnerships

Amplifying our open research to new audiences
Building on transformative collaborations—like our data meets neuroscience fellowships with the Shanahan Family Foundation and the groundbreaking technology initiative, Seattle Hub for Synthetic Biology, with the Chan Zuckerberg Initiative — Allen Impact creates innovative opportunities at the intersection of science and creativity.
Through public engagement and unique partnerships like Hip Hop Public Health, Heatherwick Studios, and Seattle 26, in 2024 we launched key initiatives to elevate the global impact of the Institute’s mission to understand life and advance health.
Impact Council
Global thought leaders and advocates who share a passion for scientific discovery with impact lend their voices to help extend our reach to new audiences. Priscilla Chan (Chan Zuckerberg Initiative), Lady Caroline Grainge, Mellody Hobson (Ariel Investments) and Sandy Weill (The Weill Family Foundation) join as founding members.
Allen Institute Alumni Network
More than 800 former employees from 16 countries and 42 states, Allen Institute alumni are a powerful extension of our community, serving as fantastic ambassadors and creating new pathways for collaboration. Alumni came together in Seattle at an open house in July to celebrate their contributions and explore new opportunities for engagement. Those attending SfN 2024 joined the Impact Reception in Chicago, bringing together current and former team members to reconnect and strengthen valuable relationships.


Impact Sessions
The Impact Sessions bring together unique voices from science, art, and technology to ignite fresh perspectives and meaningful discussion. A partnership event with the Seattle Opera delved into music’s connection to memory, while another with the San Francisco Ballet explored AI’s profound implications for humanity.
Over 300 passionate minds gathered at this year’s Allen Institute Impact Reception, hosted in the stunning Art Institute of Chicago during SfN 2024, embodying the Institute’s commitment to inclusive dialogue across communities.
Financial Summary





