Proceedings of the National Academy of Sciences of the United States of America

Oligodendrocyte precursor cells ingest axons in the mouse neocortex

Nov 29, 2022

JoAnn Buchanan, Leila Elabbady, Forrest Collman, Nikolas L. Jorstad, Trygve E. Bakken, Carolyn Ott, Jenna Glatzer, Adam A. Bleckert, Agnes L. Bodor, Derrick Brittain, Daniel J. Bumbarger, Gayathri Mahalingam, Sharmishtaa Seshamani, Casey Schneider-Mizell, Marc M. Takeno, Russel Torres, Wenjing Yin, Rebecca D. Hodge, Manuel Castro, Sven Dorkenwald, Dodam Ih, Chris S. Jordan, Nico Kemnitz, Kisuk Lee, Ran Lu, Thomas Macrina, Shang Mu, Sergiy Popovych, William M. Silversmith, Ignacio Tartavull, Nicholas L. Turner, Alyssa M. Wilson, William Wong, Jingpeng Wu, Aleksandar Zlateski, Jonathan Zung, Jennifer Lippincott-Schwartz, Ed S. Lein, H. Sebastian Seung, Dwight E. Bergles, R. Clay Reid, Nuno Maçarico da Costa

eLife

Binary and analog variation of synapses between cortical pyramidal neurons

Nov 16, 2022

Sven Dorkenwald, Nicholas L. Turner, Thomas Macrina, Kisuk Lee, Ran Lu, Jingpeng Wu, Agnes L. Bodor, Adam A. Bleckert, Derrick Brittain, Nico Kemnitz, William M. Silversmith, Dodam Ih, Jonathan Zung, Aleksandar Zlateski, Ignacio Tartavull, Szi-Chieh Yu, Sergiy Popovych, William Wong, Manuel Castro, Chris S. Jordan, Alyssa M. Wilson, Emmanouil Froudarakis, JoAnn Buchanan, Marc M. Takeno, Russel Torres, Gayathri Mahalingam, Forrest Collman, Casey M. Schneider-Mizell, Daniel J. Bumbarger, Yang Li, Lynne Becker, Shelby Suckow, Jacob Reimer, Andreas S. Tolias, Nuno Macarico da Costa, R. Clay Reid, H. Sebastian Seung

eLife

A scalable and modular automated pipeline for stitching of large electron microscopy datasets

Jul 26, 2022

Gayathri Mahalingam, Russel Torres, Daniel Kapner, Eric T. Trautman, Tim Fliss, Shamishtaa Seshamani, Eric Perlman, Rob Young, Samuel Kinn, JoAnn Buchanan, Marc M. Takeno, Wenjing Yin, Daniel J. Bumbarger, Ryder P. Gwinn, Julie Nyhus, Ed Lein, Steven J. Smith, R. Clay Reid, Khaled A. Khairy, Stephan Saalfeld, Forrest Collman, Nuno Macarico da Costa

Nature Methods

A hybrid open-top light-sheet microscope for versatile multi-scale imaging of cleared tissues

May 01, 2022

Adam K. Glaser, Kevin W. Bishop, Lindsey A. Barner, Etsuo A. Susaki, Shimpei I. Kubota, Gan Gao, Robert B. Serafin, Pooja Balaram, Emily Turschak, Philip R. Nicovich, Hoyin Lai, Luciano A. G. Lucas, Yating Yi, Eva K. Nichols, Hongyi Huang, Nicholas P. Reder, Jasmine J. Wilson, Ramya Sivakumar, Elya Shamskhou, Caleb R. Stoltzfus, Xing Wei, Andrew K. Hempton, Marko Pende, Prayag Murawala, Hans-Ulrich Dodt, Takato Imaizumi, Jay Shendure, Brian J. Beliveau, Michael Y. Gerner, Li Xin, Hu Zhao, Lawrence D. True, R. Clay Reid, Jayaram Chandrashekar, Hiroki R. Ueda, Karel Svoboda, Jonathan T. C. Liu

Cell

Reconstruction of neocortex: Organelles, compartments, cells, circuits, and activity

Mar 17, 2022

Nicholas L. Turner, Thomas Macrina, J. Alexander Bae, Runzhe Yang, Alyssa M. Wilson, Casey Schneider-Mizell, Kisuk Lee, Ran Lu, Jingpeng Wu, Agnes L. Bodor, Adam A. Bleckert, Derrick Brittain, Emmanouil Froudarakis, Sven Dorkenwald, Forrest Collman, Nico Kemnitz, Dodam Ih, William M. Silversmith, Jonathan Zung, Aleksandar Zlateski, Ignacio Tartavull, Szi-Chieh Yu, Sergiy Popovych, Shang Mu, William Wong, Chris S. Jordan, Manuel Castro, JoAnn Buchanan, Daniel J. Bumbarger, Marc Takeno, Russel Torres, Gayathri Mahalingam, Leila Elabbady, Yang Li, Erick Cobos, Pengcheng Zhou, Shelby Suckow, Lynne Becker, Liam Paninski, Franck Polleux, Jacob Reimer, Andreas S. Tolias, R. Clay Reid, Nuno Maçarico da Costa, H. Sebastian Seung

eLife

Structure and function of axo-axonic inhibition

Dec 01, 2021

Casey M. Schneider-Mizell, Agnes L. Bodor, Forrest Collman, Derrick Brittain, Adam Bleckert, Sven Dorkenwald, Nicholas L. Turner, Thomas Macrina, Kisuk Lee, Ran Lu, Jingpeng Wu, Jun Zhuang, Anirban Nandi, Brian Hu, JoAnn Buchanan, Marc M. Takeno, Russel Torres, Gayathri Mahalingam, Daniel J. Bumbarger, Yang Li, Thomas Chartrand, Nico Kemnitz, William M. Silversmith, Dodam Ih, Jonathan Zung, Aleksandar Zlateski, Ignacio Tartavull, Sergiy Popovych, William Wong, Manuel Castro, Chris S. Jordan, Emmanouil Froudarakis, Lynne Becker, Shelby Suckow, Jacob Reimer, Andreas S. Tolias, Costas A. Anastassiou, H. Sebastian Seung, R. Clay Reid, Nuno Maçarico da Costa

Cell Reports

Laminar distribution and arbor density of two functional classes of thalamic inputs to primary visual cortex

Oct 12, 2021

Jun Zhuang, Yun Wang, Naveen D. Ouellette, Emily E. Turschak, Rylan S. Larsen, Kevin T. Takasaki, Tanya L. Daigle, Bosiljka Tasic, Jack Waters, Hongkui Zeng, R. Clay Reid

Neural Networks: The Official Journal of the International Neural Network Society

Autoencoder networks extract latent variables and encode these variables in their connectomes

Sep 01, 2021

Matthew Farrell, Stefano Recanatesi, R. Clay Reid, Stefan Mihalas, Eric Shea-Brown

Nature Communications

Chromatic micromaps in primary visual cortex

Apr 19, 2021

Soumya Chatterjee, Kenichi Ohki, R. Clay Reid

Nature

Survey of spiking in the mouse visual system reveals functional hierarchy

Apr 01, 2021

Joshua H. Siegle, Xiaoxuan Jia, Séverine Durand, Sam Gale, Corbett Bennett, Nile Graddis, Greggory Heller, Tamina K. Ramirez, Hannah Choi, Jennifer A. Luviano, Peter A. Groblewski, Ruweida Ahmed, Anton Arkhipov, Amy Bernard, Yazan N. Billeh, Dillan Brown, Michael A. Buice, Nicolas Cain, Shiella Caldejon, Linzy Casal, Andrew Cho, Maggie Chvilicek, Timothy C. Cox, Kael Dai, Daniel J. Denman, Saskia E. J. de Vries, Roald Dietzman, Luke Esposito, Colin Farrell, David Feng, John Galbraith, Marina Garrett, Emily C. Gelfand, Nicole Hancock, Julie A. Harris, Robert Howard, Brian Hu, Ross Hytnen, Ramakrishnan Iyer, Erika Jessett, Katelyn Johnson, India Kato, Justin Kiggins, Sophie Lambert, Jerome Lecoq, Peter Ledochowitsch, Jung Hoon Lee, Arielle Leon, Yang Li, Elizabeth Liang, Fuhui Long, Kyla Mace, Jose Melchior, Daniel Millman, Tyler Mollenkopf, Chelsea Nayan, Lydia Ng, Kiet Ngo, Thuyahn Nguyen, Philip R. Nicovich, Kat North, Gabriel Koch Ocker, Doug Ollerenshaw, Michael Oliver, Marius Pachitariu, Jed Perkins, Melissa Reding, David Reid, Miranda Robertson, Kara Ronellenfitch, Sam Seid, Cliff Slaughterbeck, Michelle Stoecklin, David Sullivan, Ben Sutton, Jackie Swapp, Carol Thompson, Kristen Turner, Wayne Wakeman, Jennifer D. Whitesell, Derric Williams, Ali Williford, Rob Young, Hongkui Zeng, Sarah Naylor, John W. Phillips, R. Clay Reid, Stefan Mihalas, Shawn R. Olsen, Christof Koch

eLife

Relationship between simultaneously recorded spiking activity and fluorescence signal in GCaMP6 transgenic mice

Mar 08, 2021

Lawrence Huang, Peter Ledochowitsch, Ulf Knoblich, Jérôme Lecoq, Gabe J. Murphy, R. Clay Reid, Saskia Ej de Vries, Christof Koch, Hongkui Zeng, Michael A. Buice, Jack Waters, Lu Li

Nature Communications

A petascale automated imaging pipeline for mapping neuronal circuits with high-throughput transmission electron microscopy

Oct 02, 2020

Wenjing Yin, Derrick Brittain, Jay Borseth, Marie E. Scott, Derric Williams, Jedediah Perkins, Christopher S. Own, Matthew Murfitt, Russel M. Torres, Daniel Kapner, Gayathri Mahalingam, Adam Bleckert, Daniel Castelli, David Reid, Wei-Chung Allen Lee, Brett J. Graham, Marc Takeno, Daniel J. Bumbarger, Colin Farrell, R. Clay Reid, Nuno Macarico da Costa

Cell

The Mind of a Mouse

Sep 17, 2020

Larry F. Abbott, Davi D. Bock, Edward M. Callaway, Winfried Denk, Catherine Dulac, Adrienne L. Fairhall, Ila Fiete, Kristen M. Harris, Moritz Helmstaedter, Viren Jain, Narayanan Kasthuri, Yann LeCun, Jeff W. Lichtman, Peter B. Littlewood, Liqun Luo, John H. R. Maunsell, R. Clay Reid, Bruce R. Rosen, Gerald M. Rubin, Terrence J. Sejnowski, H. Sebastian Seung, Karel Svoboda, David W. Tank, Doris Tsao, David C. Van Essen

Nature Neuroscience

A large-scale standardized physiological survey reveals functional organization of the mouse visual cortex

Jan 01, 2020

Saskia E. J. de Vries, Jerome A. Lecoq, Michael A. Buice, Peter A. Groblewski, Gabriel K. Ocker, Michael Oliver, David Feng, Nicholas Cain, Peter Ledochowitsch, Daniel Millman, Kate Roll, Marina Garrett, Tom Keenan, Leonard Kuan, Stefan Mihalas, Shawn Olsen, Carol Thompson, Wayne Wakeman, Jack Waters, Derric Williams, Chris Barber, Nathan Berbesque, Brandon Blanchard, Nicholas Bowles, Shiella D. Caldejon, Linzy Casal, Andrew Cho, Sissy Cross, Chinh Dang, Tim Dolbeare, Melise Edwards, John Galbraith, Nathalie Gaudreault, Terri L. Gilbert, Fiona Griffin, Perry Hargrave, Robert Howard, Lawrence Huang, Sean Jewell, Nika Keller, Ulf Knoblich, Josh D. Larkin, Rachael Larsen, Chris Lau, Eric Lee, Felix Lee, Arielle Leon, Lu Li, Fuhui Long, Jennifer Luviano, Kyla Mace, Thuyanh Nguyen, Jed Perkins, Miranda Robertson, Sam Seid, Eric Shea-Brown, Jianghong Shi, Nathan Sjoquist, Cliff Slaughterbeck, David Sullivan, Ryan Valenza, Casey White, Ali Williford, Daniela M. Witten, Jun Zhuang, Hongkui Zeng, Colin Farrell, Lydia Ng, Amy Bernard, John W. Phillips, R. Clay Reid, Christof Koch

Journal of Colloid and Interface Science

Transport and trapping of nanosheets via hydrodynamic forces and curvature-induced capillary quadrupolar interactions

Dec 01, 2018

Timothy J. Lee, Colby F. Lewallen, Daniel J. Bumbarger, Peter J. Yunker, R. Clay Reid, Craig R. Forest

PLoS computational biology

Visual physiology of the layer 4 cortical circuit in silico

Nov 01, 2018

Anton Arkhipov, Nathan W. Gouwens, Yazan N. Billeh, Sergey Gratiy, Ramakrishnan Iyer, Ziqiang Wei, Zihao Xu, Reza Abbasi-Asl, Jim Berg, Michael Buice, Nicholas Cain, Nuno da Costa, Saskia de Vries, Daniel Denman, Severine Durand, David Feng, Tim Jarsky, Jérôme Lecoq, Brian Lee, Lu Li, Stefan Mihalas, Gabriel K. Ocker, Shawn R. Olsen, R. Clay Reid, Gilberto Soler-Llavina, Staci A. Sorensen, Quanxin Wang, Jack Waters, Massimo Scanziani, Christof Koch

Nature Neuroscience

Nontoxic, double-deletion-mutant rabies viral vectors for retrograde targeting of projection neurons

Apr 01, 2018

Soumya Chatterjee, Heather A. Sullivan, Bryan J. MacLennan, Ran Xu, YuanYuan Hou, Thomas K. Lavin, Nicholas E. Lea, Jacob E. Michalski, Kelsey R. Babcock, Stephan Dietrich, Gillian A. Matthews, Anna Beyeler, Gwendolyn G. Calhoon, Gordon Glober, Jennifer D. Whitesell, Shenqin Yao, Ali Cetin, Julie A. Harris, Hongkui Zeng, Kay M. Tye, R. Clay Reid, Ian R. Wickersham

eLife

Mouse color and wavelength-specific luminance contrast sensitivity are non-uniform across visual space

Jan 10, 2018

Daniel J. Denman, Jennifer A. Luviano, Douglas R. Ollerenshaw, Sissy Cross, Derric Williams, Michael A. Buice, Shawn R. Olsen, R. Clay Reid

PloS One

Large-scale neuroanatomy using LASSO: Loop-based Automated Serial Sectioning Operation

Jan 01, 2018

Timothy J. Lee, Aditi Kumar, Aishwarya H. Balwani, Derrick Brittain, Sam Kinn, Craig A. Tovey, Eva L. Dyer, Nuno M. da Costa, R. Clay Reid, Craig R. Forest, Daniel J. Bumbarger

The Journal of Neuroscience: The Official Journal of the Society for Neuroscience

Spatial Organization of Chromatic Pathways in the Mouse Dorsal Lateral Geniculate Nucleus

Feb 01, 2017

Daniel J. Denman, Joshua H. Siegle, Christof Koch, R. Clay Reid, Timothy J. Blanche

The Journal of Neuroscience: The Official Journal of the Society for Neuroscience

A Comparison of Visual Response Properties in the Lateral Geniculate Nucleus and Primary Visual Cortex of Awake and Anesthetized Mice

Nov 30, 2016

Séverine Durand, Ramakrishnan Iyer, Kenji Mizuseki, Saskia de Vries, Stefan Mihalas, R. Clay Reid

Proceedings of the National Academy of Sciences of the United States of America

Inferring cortical function in the mouse visual system through large-scale systems neuroscience

Jul 05, 2016

Michael Hawrylycz, Costas Anastassiou, Anton Arkhipov, Jim Berg, Michael Buice, Nicholas Cain, Nathan W. Gouwens, Sergey Gratiy, Ramakrishnan Iyer, Jung Hoon Lee, Stefan Mihalas, Catalin Mitelut, Shawn Olsen, R. Clay Reid, Corinne Teeter, Saskia de Vries, Jack Waters, Hongkui Zeng, Christof Koch, MindScope

Nature

Anatomy and function of an excitatory network in the visual cortex

Apr 21, 2016

Wei-Chung Allen Lee, Vincent Bonin, Michael Reed, Brett J. Graham, Greg Hood, Katie Glattfelder, R. Clay Reid

Neuron

Transgenic mice for intersectional targeting of neural sensors and effectors with high specificity and performance

Mar 04, 2015

Linda Madisen, Aleena R. Garner, Daisuke Shimaoka, Amy S. Chuong, Nathan C. Klapoetke, Lu Li, Alexander van der Bourg, Yusuke Niino, Ladan Egolf, Claudio Monetti, Hong Gu, Maya Mills, Adrian Cheng, Bosiljka Tasic, Thuc Nghi Nguyen, Susan M. Sunkin, Andrea Benucci, Andras Nagy, Atsushi Miyawaki, Fritjof Helmchen, Ruth M. Empson, Thomas Knöpfel, Edward S. Boyden, R. Clay Reid, Matteo Carandini, Hongkui Zeng

Nature Protocols

Removable cranial windows for long-term imaging in awake mice

Nov 01, 2014

Glenn J. Goldey, Demetris K. Roumis, Lindsey L. Glickfeld, Aaron M. Kerlin, R. Clay Reid, Vincent Bonin, Dorothy P. Schafer, Mark L. Andermann

Current Opinion in Neurobiology

A mouse model of higher visual cortical function

Feb 01, 2014

Lindsey L. Glickfeld, R. Clay Reid, Mark L. Andermann

Scientific and statistical database management: International Conference, SSDBM ...: proceedings. International Conference on Scientific and Statistical Database Management

The Open Connectome Project Data Cluster: Scalable Analysis and Vision for High-Throughput Neuroscience

Jan 01, 2013

Randal Burns, William Gray Roncal, Dean Kleissas, Kunal Lillaney, Priya Manavalan, Eric Perlman, Daniel R. Berger, Davi D. Bock, Kwanghun Chung, Logan Grosenick, Narayanan Kasthuri, Nicholas C. Weiler, Karl Deisseroth, Michael Kazhdan, Jeff Lichtman, R. Clay Reid, Stephen J. Smith, Alexander S. Szalay, Joshua T. Vogelstein, R. Jacob Vogelstein

eLife

Expansion-assisted selective plane illumination microscopy for nanoscale imaging of centimeter-scale tissues

Adam Glaser, Jayaram Chandrashekar, Sonya Vasquez, Cameron Arshadi, Naveen Ouellette, Xiaoyun Jiang, Judith Baka, Gabor Kovacs, Micah Woodard, Sharmishtaa Seshamani, Kevin Cao, Nathan Clack, Andrew Recknagel, Anna Grim, Pooja Balaram, Emily Turschak, Marcus Hooper, Alan Liddell, John Rohde, Ayana Hellevik, Kevin Takasaki, Lindsey Erion Barner, Molly Logsdon, Chris Chronopoulos, Saskia de Vries, Jonathan Ting, Steve Perlmutter, Brian Kalmbach, Nikolai Dembrow, Bosiljka Tasic, R. Clay Reid, David Feng, Karel Svoboda

eNeuro

Capillary-Based and Stokes-Based Trapping of Serial Sections for Scalable 3D-EM Connectomics

Timothy J. Lee, Mighten C. Yip, Aditi Kumar, Colby F. Lewallen, Daniel J. Bumbarger, R. Clay Reid, Craig R. Forest