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Mouse study uncovers links between unsung brain cells and Huntington’s disease — and possible path for human therapies

October 21, 2020

Astrocytes, once thought of as inert ‘brain glue,’ may turn out to be key players in Huntington’s and other neurodegenerative diseases.

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New cell line lets researchers use CRISPR to reversibly switch off genes

October 20, 2020

‘CRISPR interference’ technique enables study of basic cell biology and disease in human stem cells

Press Release

The Paul G. Allen Frontiers Group Announces New Allen Distinguished Investigators

October 8, 2020

Collaborative projects funded by the awards will address important questions about neurodegenerative disease, nucleus biology, and protein turnover

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Mouse study uncovers links between unsung brain cells and Huntington’s disease — and possible path for human therapies

October 21, 2020

Astrocytes, once thought of as inert ‘brain glue,’ may turn out to be key players in Huntington’s and other neurodegenerative diseases.

In the News

2 scientists win Nobel chemistry prize for gene-editing tool

Associated Press

October 7, 2020

Allen Distinguished Investigator Jennifer A. Doudna and her colleague Emmanuelle Charpentier won for developing CRISPR-cas9, a very simple technique for cutting a gene at a specific spot.

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Accelerating Frontier Science | The Paul G. Allen Frontiers Group

October 7, 2020

The Paul G. Allen Frontiers Group seeks pioneers and explorers willing to make big advancements, take risks, ask questions, be tenacious, and have curiosity to change the face of biology.

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News from The Paul G. Allen Frontiers Group: August 2020

August 20, 2020

Highlights include: Testing treatments aimed at Alzheimer's for Covid-19 patients, how funding basic neuroscience research can support Covid-19 research, a new study by AHA-Allen Initiative awardee Tony Wyss-Coray, and more.

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Could treatments aimed at Alzheimer’s disease help combat COVID-19?

August 5, 2020

A team of cardiology researchers had a creative idea for a new way to treat dementia. Now they think it could help coronavirus patients too. 

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Old age changes the way blood accesses the brain

July 7, 2020

A new study in mice shows that contrary to longstanding dogma, blood proteins easily cross into the brain, but transport machinery breaks down with age

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News from The Paul G. Allen Frontiers Group: May 2020

May 20, 2020

Highlights include an important message for our research community, a face mask that detects coronavirus, our new video series #ScienceMatters, and more.

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Scientists are working on a face mask that detects coronavirus

April 23, 2020

Q&A with James Collins, Ph.D., a bioengineer who is developing a diagnostic face mask that signals if the wearer is infected with COVID-19

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Random chance in early brain development sets adult fruit flies’ personalities

March 24, 2020

Brain wiring asymmetry established as animals grow influences their innate behavior, a new study finds

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An important message for our Allen Distinguished Investigators and Allen Discovery Centers

March 18, 2020

Thoughts and our continued support amidst the COVID-19 pandemic

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News from The Paul G. Allen Frontiers Group: January 2020

January 30, 2020

Highlights include upcoming events, new research by Allen Distinguished Investigator Christian Steidl, M.D., new Frontier Voices videos, and more.

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Hodgkin lymphoma recruits and trains immune cells to help it thrive

January 14, 2020

Study also highlights possible new targets for treatment, how to better tailor cancer therapies for individual patients

News

News from The Paul G. Allen Frontiers Group: November 2019

November 7, 2019

Highlights include newly awarded Allen Distinguished Investigators, a DREAM Challenge on developmental lineage, research on brain-intestine circadian signals, and more.

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A computational challenge to help developmental biology

October 1, 2019

Q&A with the scientists and organizers behind a new competition to use machine learning to reconstruct an entire animal’s developmental lineage

News

How the gut keeps time — and keeps us healthy

September 18, 2019

New study identifies brain-intestine circadian signals that could underlie health problems related to night shift work and poor sleep

News

News from The Paul G. Allen Frontiers Group: August 2019

August 6, 2019

Highlights include a roundup of our recent Exploring Frontiers symposiums on modeling and morphogensis, a funding initiative for new cancer initiatives and more. 

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