Fred Hutch

Team

Stanley Riddell, M.D.

Fred Hutchinson Cancer Research Center

Dr. Stanley Riddell is a Member in the Program in Immunology and Scientific Director of the Immunotherapy Integrated Research Center at Fred Hutchinson Cancer Research Center, and Professor in the Department of Medicine at the University of Washington. His research focuses on understanding how T cells respond to pathogens and tumors, and on the development and clinical application of adoptive T cell therapy for cancer by genetically modifying specific subsets of T cells with natural and synthetic receptors to instruct them to recognize tumor cells. His lab led the first trials of antigen-specific T cell therapy in humans and the first trials to administer genetically modified antigen-specific T cells. Dr. Riddell has received numerous honors, including the E. Donnall Thomas award from the American Society of Blood and Marrow Transplantation, a Hans Fischer Senior Fellowship from the Institute for Advanced Study at the Technical University of Munich, the Hans Messner Award from the Canadian Blood and Marrow Transplant Group, and election to the Association of American Physicians and American College of Physicians. He is an Ambassador and Distinguished Affiliate Professor at the Technical University of Munich and Virginia Hobbs Charitable Trust Research Professor of the American Cancer Society.

Raphael Gottardo, Ph.D.

Fred Hutchinson Cancer Research Center

Dr. Dr. Gottardo is a Full Member and Associate Head of the Biostatistics, Bioinformatics and Epidemiology program of the Vaccine and Infectious Disease Division at Fred Hutchinson Cancer Research Center. Additionally, he holds an affiliate professorship in the Department of Statistics at the University of Washington, where he regularly supervises graduate students. 

Dr. Gottardo’s current research interests center on the development of computational tools and statistical methods for analyzing high-dimensional data with applications to immunology, vaccine research, and immunotherapy. He is principal investigator (PI) of several grants from the National Institutes of Health (NIH), the Bill and Melinda Gates Foundation (BMGF), and the Chan-Zuckerberg Initiative (CZI). In particular, he is PI of the Vaccine and Immunology Statistical Center of the BMGF where his group contributes statistical and computational methods, data tools, and data analysis for assessing immunogenicity of a number of vaccine candidates (including HIV, TB, and malaria vaccines). Dr. Gottardo plays an important role within the NIH-funded Human Immunology Project Consortium, where he leads the development of the central database and analysis engine, ImmuneSpace (immunespace.org). Finally, he also contributes significantly to the open source bioinformatics community (particularly in the area of single-cell analysis) via his active roles in the Bioconductor project, the Flow Cytometry Critical Assessment of Population (FlowCAP) project, and the Human Cell Atlas. In 2018 he received the Mortimer Spiegelman Award, which honors a statistician below the age of 40 in the calendar year of the award who has made outstanding contributions to health statistics, especially public health statistics.

Philip Greenberg, M.D.

Fred Hutchinson Cancer Research Center

Dr. Phil Greenberg is Professor of Medicine and Immunology at the University of Washington, and Head of the Program in Immunology at Fred Hutchinson Cancer Research Center. His research has focused on elucidating fundamental principles of T cell and tumor interactions; developing cellular and molecular approaches to manipulate T cell immunity; and translating insights from the lab to treatment of cancer patients, with emphasis on adoptive therapy with genetically engineered T cells. He has authored more than 290 manuscripts and has received many honors including the William B. Coley Award for Distinguished Research in Tumor Immunology from the Cancer Research Institute, the Team Science Award for Career Achievements from the Society for Immunotherapy of Cancer, the Seattle Business Magazine Gold Award for Leader in Health Care, the Society for Immunotherapy of Cancer 2018 Richard Smalley Memorial Award, and election to the American Society of Clinical Investigation, the Association of American Physicians, the American College of Physicians, and the American Association for the Advancement of Science. He has been a member of multiple scientific advisory committees and editorial boards, and is currently a member of the Board of Directors of the American Association for Cancer Research (AACR) and an Editor-In-Chief of Cancer Immunology Research