Team

Staff Profiles

Suhas V. Vasaikar, Ph.D.

Senior Scientist

suhas.vasaikar@alleninstitute.org

Suhas Vasaikar is a computational biologist, specialized in cancer research and integrative multiomics analysis. Currently, he is a Senior Scientist in the Informatics & Computational Biology department at the Allen institute for Immunology. He is focused on integrative biology at single cell level and discovering novel mechanistic insights associated with human disease-immune interactions.

Dr. Vasaikar’s elite standing in the biomedical science field is well supported by his comprehensive academic and research experience. For his educational background, he earned his M.Sc. at the Savitribai Phule Pune University (formerly University of Pune) and his Ph.D. at the Indian Institute of Technology Delhi. After completing his academic training, he conducted research at notable institutes around the world including the Karolinska Institute in Sweden, Vanderbilt University’s Department of Biomedical Informatics, Baylor College of Medicine’s Lester and Sue Smith Breast Cancer Center and MD Anerson Cancer Research Center. His original research on topics like integrated multiomics analysis, proteogenomics analysis for use in identifying cancer biomarkers, and breast cancer tumor chemoresistance has been published within prestigious journals and conference proceedings, cited extensively by his peers, and funded by renowned federal, state, and non-profit organizations.

Over his research experience, he has published near 30 journal articles in peer review journals including Cell, Nature Communications, JNCI, British Journal of Cancer and BMC Neuroscience, and reviewed more than 40 research articles. He was a part of NCI CPTAC team, worked on majorly Colon cancer, kidney cancer, endometrial cancer and lung cancer which resulted in proteogenomic understanding of cancer and therapeutic opportunities. Apart from publications, he has developed and/or worked on several online tools which include LinkedOmics, NeuroDNet, WebGestalt, and EMTome online tools which are used by clinicians, researchers in US and across globe.

Research

Research Interests

My research interests lie in bioinformatics, systems biology, biomedical Informatics, cancer cell signaling research and neuroscience.

Expertise

  • Systems biology
  • Complutatinal biology
  • Integrative multi-omics
  • Cancer

Research Programs

  • Longitudinal healthy cohort, COVID-19
  • Multiple Myeloma
  • Rheumatoid Arthritis

Selected Publications

Proteogenomic Characterization Reveals Therapeutic Vulnerabilities in Lung Adenocarcinoma

Cell
July 9, 2020

MA Gillette, S Satpathy, S Cao, S Dhanasekaran, S Vasaikar, K Krug, F Petralia, Y Li, W-W Liang, B Reva, R Hong, S Savage, G Getz, QK Li, B Zhang, H Rodriguez, K Ruggles, AI Robles, KC Clauser, R Govindan, P Wang, A Nesvizhskii, L Ding, DR Mani, SA Carr

Proteogenomic Characterization of Endometrial Carcinoma

Cell
February 20, 2020

Dou Y, Kawaler EA, Cui Zhou D, Gritsenko MA, Huang C, Blumenberg L, Karpova A, Petyuk VA, Savage SR, Satpathy S, Liu W, Wu Y, Tsai CF, Wen B, Li Z, Cao S, Moon J, Shi Z, Cornwell M, Wyczalkowski MA, Chu RK, Vasaikar S, Zhou H, Gao Q, Moore RJ, Li K, Sethuraman S, Monroe ME, Zhao R, Heiman D, Krug K, Clauser K, Kothadia R, Maruvka Y, Pico AR, Oliphant AE, Hoskins EL, Pugh SL, Beecroft SJI, Adams DW, Jarman JC, Kong A, Chang HY, Reva B, Liao Y, Rykunov D, Colaprico A, Chen XS, Czekanski A, Jedryka M, Matkowski R, Wiznerowicz M, Hiltke T, Boja E, Kinsinger CR, Mesri M, Robles AI, Rodriguez H, Mutch D, Fuh K, Ellis MJ, DeLair D, Thiagarajan M, Mani DR, Getz G, Noble M, Nesvizhskii AI, Wang P, Anderson ML, Levine DA, Smith RD, Payne SH, Ruggles KV, Rodland KD, Ding L, Zhang B, Liu T, Fenyo D

Integrated Proteogenomic Characterization of Clear Cell Renal Cell Carcinoma

Cell
January 9, 2020

Clark DJ, Dhanasekaran SM, Petralia F, Pan J, Song X, Hu Y, da Veiga Leprevost F, Reva B, Lih TM, Chang HY, Ma W, Huang C, Ricketts CJ, Chen L, Krek A, Li Y, Rykunov D, Li QK, Chen LS, Ozbek U, Vasaikar S, Wu Y, Yoo S, Chowdhury S, Wyczalkowski MA, Ji J, Schnaubelt M, Kong A, Sethuraman S, Avtonomov DM, Ao M, Colaprico A, Cao S, Cho KC, Kalayci S, Ma S, Liu W, Ruggles K, Calinawan A, Gumus ZH, Geiszler D, Kawaler E, Teo GC, Wen B, Zhang Y, Keegan S, Li K, Chen F, Edwards N, Pierorazio PM, Chen XS, Pavlovich CP, Hakimi AA, Brominski G, Hsieh JJ, Antczak A, Omelchenko T, Lubinski J, Wiznerowicz M, Linehan WM, Kinsinger CR, Thiagarajan M, Boja ES, Mesri M, Hiltke T, Robles AI, Rodriguez H, Qian J, Fenyo D, Zhang B, Ding L, Schadt E, Chinnaiyan AM, Zhang Z, Omenn GS, Cieslik M, Chan DW, Nesvizhskii AI, Wang P, Zhang H

Proteogenomic Analysis of Human Colon Cancer Reveals New Therapeutic Opportunities

Cell
May 2, 2019

Vasaikar S, Huang C, Wang X, Petyuk VA, Savage SR, Wen B, Dou Y, Zhang Y, Shi Z, Arshad OA, Gritsenko MA, Zimmerman LJ, McDermott JE, Clauss TR, Moore RJ, Zhao R, Monroe ME, Wang YT, Chambers MC, Slebos RJC, Lau KS, Mo Q, Ding L, Ellis M, Thiagarajan M, Kinsinger CR, Rodriguez H, Smith RD, Rodland KD, Liebler DC, Liu T, Zhang B

EPHB2 carried on small extracellular vesicles induces tumor angiogenesis via activation of ephrin reverse signaling

JCI Insight
December 5, 2019

Sato S, Vasaikar S, Eskaros A, Kim Y, Lewis JS, Zhang B, Zijlstra A, Weaver AM

LinkedOmics: analyzing multi-omics data within and across 32 cancer types

Nucleic Acids
January 4, 2018

Vasaikar SV, Straub P, Wang J, Zhang B