Disease Models (2019 & 2020)
For many disease states, the fundamental mechanisms and biology underlying multicellular development and regeneration are still a mystery. Given limitations with current animal models, several research groups are now turning to human induced pluripotent stem cells to better model biological processes inherent in human health and disease. These Allen Distinguished Investigators are using human stem cells in innovative studies that address important outstanding questions in human disease and basic biology and will generate new methods to benefit others in the scientific community.
Affiliated Projects
Disease Models (2019 & 2020)
Human iPSC Models of Metabolic and Digestive Diseases
Disease Models (2019 & 2020)
Reading and writing cell histories: New genomic technologies to unlock cell programming
Disease Models (2019 & 2020)
Simulating the Gut-Brain Axis using iPSC and Organ-Chip Technology: A New Model of Parkinson's Disease
Disease Models (2019 & 2020)
Early manifestations of subcellular defects in neurodegenerative diseases