Nuclear Biophysics (2018)

Nuclear biophysics is an emerging research field that seeks to understand the special physics inside the nucleus, the cellular compartment that houses DNA. In the past five years, there’s been a growing appreciation that DNA and other molecules inside the nucleus are organized into physical states that researchers think of as akin to a microscopic lava lamp or as different phases of the same substance, like ice and water. These physical states may influence everything from how the cell makes proteins to how cancer forms to how well certain drugs function.