Extracellular Matrix (2017)

Two ADI awards were given together with the American Heart Association to fund studies of the extracellular matrix, the proteins and molecules that make up a "living glue" surrounding our cells, as it relates to the human heart. The extracellular matrix is a network of protein fibers in all tissues, including the heart, that can store and transmit information across months, years and decades-well past the lives of many individual cells. Knowledge about how the matrix instructs cells to behave and how it stores long-term memory may change the way we think of and treat cardiovascular disease, making it a crucial frontier topic in heart research.

The projects are co-funded with the American Heart Association at $1.5 million each over three years.