Cell Science 2017 Year in Review

December 18, 2017

It has been another full and exciting year for the Allen Institute for Cell Science. Here are some highlights from 2017.

We launched the Allen Cell Explorer.

In April, we announced the launch of the Allen Cell Explorer: a one-of-a-kind portal and dynamic digital window into the human cell. The website combines large-scale 3D imaging data, the first application of deep learning to create predictive models of cell organization, gene edited human stem cell lines and a growing suite of powerful tools.

We updated our resources with new data and cell lines.

We have been keeping our resources up to date with additional lines in our Allen Cell Collection, new image data, plasmids and tutorials. View a summary of our updates over the past year here.

We showed users how to navigate our data.

We created two new tutorials to show users how to get the most out of two aspects of the Allen Cell Explorer: the Allen Cell Collection and the 3D Cell Viewer.

We learned how people are using our resources.

Researchers around the world are already beginning to use our cell lines and data to expand their work. Watch the first installment of our series Cell Shorts that explores how our resources are enabling science around the globe.

We announced the 3D CellProfiler.

The Broad Institute of MIT and Harvard and the Allen Institute for Cell Science announced the release of CellProfiler 3.0. CellProfiler is a free, open-source quantitative image analysis package developed by Broad Institute scientist and Imaging Platform director Anne Carpenter, Ph.D., and her team. CellProfiler 3.0 is the first version that can identify objects in 3D images volumetrically. Learn more in our news story.

We hosted the Seattle Cell Science Symposium.

We were pleased to host the second annual Seattle Cell Science Symposium: a full-day event showcasing research in the Seattle-area cell biology community. Watch videos and view photos on our event page.

We attended conferences and created webinars.

We continued our outreach to the scientific community with a presence at ASCB and ISSCR, and shared a webinar through StemCell Technologies. View more on our event page.

We published scientific papers.

We shared analyses on data we have generated, including our integrated cell model and label free imaging method, and information on the cell lines we create in two new scientific publications, linked below.

Systematic gene tagging using CRISPR/Cas9 in human stem cells to illuminate cell organization
Molecular Biology of the Cell (MBoC), August 16, 2017. Roberts B, Haupt A, Tucker A, Grancharova T, Arakaki J, Fuqua MA, Nelson A, Hookway C, Ludmann SA, Mueller IA, Yang R, Horwitz AR, Rafelski SM, Gunawardane RN.

Three dimensional cross-modal image inference: label-free methods for subcellular structure prediction
bioRxiv pre-print, November 2017. Ounkomol C, Fernandes DA, Seshamani S, Maleckar MM, Collman F, Johnson GR.

For more of our year in review, visit the Brain Science and Frontiers Group recaps, and read our most recent Annual Report.