Angel Nelson
Principal Research Associate
Angel is a Research Associate in the Stem Cell and Gene Editing group. Her current work focuses on developing tools and methods to study early steps of cardiomyocyte differentiation of the gene-edited human induced pluripotent stem cells (hiPSCs) produced within the group. She originally joined the Allen Institute for Brain Science as a Research Associate in the in vitro Human Cell Types team, where she studied differentiation of stem cells into neural lineages. Angel’s broad experience with stem cells and embryology spans from working in academic labs making genetically engineered mice, to clinical applications in a fertility clinic, to developing a novel human stem cell line in the naïve state. She has extensive experience working with many different stem cell lines in a variety of contexts. Angel completed her Bachelor of Science in Microbiology and Bachelor of Arts in Psychology at the University of Washington.
Selected Publications
Fluorescent Gene Tagging of Transcriptionally Silent Genes in hiPSCs
Stem Cell Reports
April 4, 2019
Roberts B, Hendershott MC, Arakaki J, Gerbin KA, Malik H, Nelson A, Gehring J, Hookway C, Ludmann SA, Yang R, Haupt A, Grancharova T, Valencia V, Fuqua MA, Tucker A, Rafelski SM, Gunawardane RN
bioRxiv
June 9, 2018
Roberts B, Arakaki J, Gerbin KA, Malik H, Nelson A, Hendershott MC, Hookway C, Ludmann SA, Mueller IA, Yang R, Rafelski SM, Gunawardane RN
Systematic gene tagging using CRISPR/Cas9 in human stem cells to illuminate cell organization
Molecular Biology of the Cell
October 15, 2017
Roberts B, Haupt A, Tucker A, Grancharova T, Arakaki J, Fuqua MA, Nelson A, Hookway C, Ludmann SA, Mueller IA, Yang R, Horwitz R, Rafelski SM, Gunawardane RN
A Single-Cell Roadmap of Lineage Bifurcation in Human ESC Models of Embryonic Brain Development
Cell Stem Cell
October 27, 2016
Yao Z, Mich JK, Ku S, Menon V, Krostag A-R, Martinez RA, Furchtgott L, Mulholland H, Bort S, Fuqua MA, Gregor BW, Hodge RD, Jayabalu A, May RC, Melton S, Nelson AM, Ngo NK, Shapovalova NV, Shehata SI, Smith MW, Tait LJ, Thompson CL, Thomsen ER, Ye C, Glass IA, Kaykas A, Yao S, Phillips JW, Grimley JS, Levi BP, Wang Y, Ramanathan S
Genome engineering of isogenic human ES cells to model autism disorders
Nucleic Acids Research
March 11, 2015
Martinez RA, Stein JL, Krostag AR, Nelson AM, Marken JS, Menon V, May RC, Yao Z, Kaykas A, Geschwind DH, Grimley JS
Fixed single-cell transcriptomic characterization of human radial glial diversity
Nature Methods
November 16, 2015
Thomsen ER, Mich JK, Yao Z, Hodge RD, Doyle AM, Jang S, Shehata SI, Nelson AM, Shapovalova NV, Levi BP, Ramanathan S