Team

Staff Profiles

Angel Nelson

Principal Research Associate

angeln@alleninstitute.org

Angel is a Research Associate in the Stem Cell and Gene Editing group.  Her current work focuses on developing tools and methods to study early steps of cardiomyocyte differentiation of the gene-edited human induced pluripotent stem cells (hiPSCs) produced within the group.  She originally joined the Allen Institute for Brain Science as a Research Associate in the in vitro Human Cell Types team, where she studied differentiation of stem cells into neural lineages. Angel’s broad experience with stem cells and embryology spans from working in academic labs making genetically engineered mice, to clinical applications in a fertility clinic, to developing a novel human stem cell line in the naïve state. She has extensive experience working with many different stem cell lines in a variety of contexts. Angel completed her Bachelor of Science in Microbiology and Bachelor of Arts in Psychology at the University of Washington.

Selected Publications

Fluorescent Gene Tagging of Transcriptionally Silent Genes in hiPSCs

Stem Cell Reports
April 4, 2019

Roberts B, Hendershott MC, Arakaki J, Gerbin KA, Malik H, Nelson A, Gehring J, Hookway C, Ludmann SA, Yang R, Haupt A, Grancharova T, Valencia V, Fuqua MA, Tucker A, Rafelski SM, Gunawardane RN

Scarless gene tagging of transcriptionally silent genes in hiPSCs to visualize cardiomyocyte sarcomeres in live cells

bioRxiv
June 9, 2018

Roberts B, Arakaki J, Gerbin KA, Malik H, Nelson A, Hendershott MC, Hookway C, Ludmann SA, Mueller IA, Yang R, Rafelski SM, Gunawardane RN

Systematic gene tagging using CRISPR/Cas9 in human stem cells to illuminate cell organization

Molecular Biology of the Cell
October 15, 2017

Roberts B, Haupt A, Tucker A, Grancharova T, Arakaki J, Fuqua MA, Nelson A, Hookway C, Ludmann SA, Mueller IA, Yang R, Horwitz R, Rafelski SM, Gunawardane RN

A Single-Cell Roadmap of Lineage Bifurcation in Human ESC Models of Embryonic Brain Development

Cell Stem Cell
October 27, 2016

Yao Z, Mich JK, Ku S, Menon V, Krostag A-R, Martinez RA, Furchtgott L, Mulholland H, Bort S, Fuqua MA, Gregor BW, Hodge RD, Jayabalu A, May RC, Melton S, Nelson AM, Ngo NK, Shapovalova NV, Shehata SI, Smith MW, Tait LJ, Thompson CL, Thomsen ER, Ye C, Glass IA, Kaykas A, Yao S, Phillips JW, Grimley JS, Levi BP, Wang Y, Ramanathan S

Genome engineering of isogenic human ES cells to model autism disorders

Nucleic Acids Research
March 11, 2015

Martinez RA, Stein JL, Krostag AR, Nelson AM, Marken JS, Menon V, May RC, Yao Z, Kaykas A, Geschwind DH, Grimley JS

Fixed single-cell transcriptomic characterization of human radial glial diversity

Nature Methods
November 16, 2015

Thomsen ER, Mich JK, Yao Z, Hodge RD, Doyle AM, Jang S, Shehata SI, Nelson AM, Shapovalova NV, Levi BP, Ramanathan S