Workshop on Neurogenetic Tools: Using Mouse Models to Study Human Neurodegenerative Disease

May 8, 2017 - May 12, 2017

  • The Jackson Laboratory, Bar Harbor ME
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This JAX course will focus on the use of the innovative tools and methods, specifically in the laboratory mouse, for answering questions of neuron and circuit function and disease mechanisms during neurodegeneration.  This course will employ both didactic and hands-on instruction in both laboratory techniques and bioinformatics.

This five day workshop is focused on the use of the mouse in neuroscience studies, particularly neurodegenerative disease. It will survey current methods in the field with a strong emphasis on neurogenetic tools. Workshops topics will include but are not limited to:

  • peripheral and central nervous system disease models
  • optogenetics
  • tissue clearing methods
  • CRE/LOX systems
  • single cell genomics
  • development of disease models using CRISPR/Cas9
  • optopatch system
  • bioinformatic databases and data analysis tools
  • using viral vectors for gene delivery and tracing
  • behavioral analysis
  • forward and systems genetics approaches to complex trait analysis