Workshop on Neurogenetic Tools: Using Mouse Models to Study Human Disease

June 21, 2016 - June 24, 2016

  • The Jackson Laboratory, Bar Harbor, ME

This new JAX course will focus on the use of the innovative tools and methods, specifically in the laboratory mouse, for answering questions of neuron and circuit function and disease mechanisms.  This course will employ both didactic and hands-on instruction in both laboratory techniques and bioinformatics.

This 3.5 day pilot workshop is focused on the use of the mouse in neuroscience studies.  It will survey current methods in the field with a strong emphasis on neurogenetic tools.  Leaders in the field will discuss and lead laboratory workshops on topics including:

  • peripheral and central nervous system disease models
  • optogenetics
  • tissue clearing methods
  • live animal deep brain imaging
  • CRE/LOX systems
  • development of disease models using CRISPR/Cas9
  • bioinformatic databases and data analysis tools
  • using viral vectors for gene delivery and tracing
  • behavioral analysis
  • forward and systems genetics approaches to complex trait analysis