Team

Staff Profiles

Travis Hage

Scientist II

travish@alleninstitute.org

Travis Hage joined the Allen Institute in 2016 to help perform electrophysiology and photostimulation experiments to unravel cortical microcircuitry. Travis received his undergraduate training in Biology at the University of Texas in Austin. As part of a senior thesis with Dr. Nace Golding, Travis helped characterize the cellular physiology of an auditory brainstem circuit. Travis then went on to graduate school at Washington University in St. Louis. As a student in Lawrence Salkoff’s laboratory he used whole-cell electrophysiology and single channel recordings to uncover unique aspects of potassium channel and sodium channel function. Before joining the Allen Institute, Travis was a postdoc in Dr. Zayd Khaliq’s lab at the National Institutes of Health Intramural Research Program. There, he used a combination of electrophysiology, two photon imaging and photostimulation to study cellular physiology and synaptic integration in midbrain dopamine neurons.

Research

Research Interests

My long-term research interests are centered around understanding the rules by which neurons transform their inputs into their outputs. There are many components to this subject, but chief among them is understanding the patterns of connectivity amongst different classes and types of neurons. I am interested in combining whole-cell electrophysiology with modern imaging and optogenetic techniques to perform experiments that would not be possible if utilizing these methods in isolation. Working at the Allen Institute also provides the unique opportunity to test new genetic tools and work across teams to obtain multi-modal datasets on the same pieces of tissue.

Expertise

Cellular and Synaptic Physiology

Research Interests

  • Cell Types
  • Synaptic Physiology

Selected Publications

Sparse recurrent excitatory connectivity in the microcircuit of the adult mouse and human cortex

eLife
September 26, 2018

Seeman SC, Campagnola L, Davoudian PA, Hoggarth A, Hage TA, Bosma-Moody A, Baker CA, Lee, JH, Mihalas S, Teeter C, Ko AL, Ojemann JG, Gwinn RP, Silbergeld DL, Cobbs C, Phillips J, Lein E, Murphy G, Koch C, Zeng H, Jarsky T

A Suite of Transgenic Driver and Reporter Mouse Lines with Enhanced Brain-Cell-Type Targeting and Functionality

Cell
July 12, 2018

Daigle TL, Madisen L, Hage TA, Valley MT, Knoblich U, Larsen RS, Takeno MM, Huang L, Gu H, Larsen R, Mills M, Bosma-Moody A, Siverts LA, Walker M, Graybuck LT, Yao Z, Fong O, Nguyen TN, Garren E, Lenz GH, Chavarha M, Pendergraft J, Harrington J, Hirokawa KE, Harris JA, Nicovich PR, McGraw MJ, Ollerenshaw DR, Smith KA, Baker CA, Ting JT, Sunkin SM, Lecoq J, Lin MZ2, Boyden ES, Murphy GJ, da Costa NM, Waters J, Li L, Tasic B, Zeng H