Rusty Nicovich, Ph.D.
Senior Manager, Imaging
Rusty Nicovich holds a Ph.D. in Physical Chemistry from GaTech focusing on single-molecule spectroscopy and developing image analysis methods for flow analysis in microfluidics. He held a postdoc at Johns Hopkins Medical Institute investigating microtubule polymerization rates in peripheral neurons using TIRF microscopy. He made a big move to University of New South Wales in Sydney, where he started in the Biomedical Imaging Facility core overseeing the super-resolution instruments and developing image analyses for quantitative super-resolution microscopy, combinatoric labelling methods, and actin association. He then moved to the new Centre for Single Molecule Science, leading the instrument and algorithm development teams working to understand T cell activation and the assembly of molecular motors.
I like measuring things and figuring out how to measure things. This has manifested itself in a career in quantitative fluorescence microscopy and experimental design and image analysis to measure a wide range of parameters concerning an array of biological processes. Included in this is developing the instruments with the capability of performing the experiments needed while being straightforward and robust enough to be used in the biology lab.
Light microscopy, especially fluorescence microscopy and super-resolution methods. Instrument development and analysis algorithm development for fluorescence and super-resolution microscopy. A big focus is translating new techniques from the initial demonstration into a tool that can be used by a wider audience of biologists.
Anything that passes through the Imaging department. Currently a big focus is instrument development for Multiplexed FISH. IVSCC, patch-seq, cell counting, synaptic physiology, mesoscale connectomics, genetic tools and cell types all aided by the Imaging core’s capabilities.
Selected Publications View on PUBMED
July 4, 2019
Glaser AK, Reder NP, Chen Y, Yin C, Wei L, Kang S, Barner LA, Xie W, McCarty EF, Mao C, Halpern AR, Stoltzfus CR, Daniels JS, Gerner MY, Nicovich PR, Vaughan JC, True LD, Liu JTC
June 17, 2019
Gouwens NW, Sorensen SA, Berg J, Lee C, Jarsky T, Ting J, Sunkin S, Feng D, Anastassiou C, Barkan E, Bickley K, Blesie N, Braun T, Brouner K, Budzillo A, Caldejon S, Casper T, Castelli D, Chong P, Crichton K, Cuhaciyan C, Daigle T, Dalley R, Dee N, Desta T, Dingman S, Doperalski A, Dotson N, Egdorf T, Fisher M, de Frates RA, Garren E, Garwood M, Gary A, Gaudreault N, Godfrey K, Gorham M, Gu H, Habel C, Hadley K, Harrington J, Harris J, Henry A, Hill D, Josephsen S, Kebede S, Kim L, Kroll M, Lee B, Lemon T, Liu X, Long B, Mann R, McGraw M, Mihalas S, Mukora A, Murphy GJ, Ng L, Ngo K, Nguyen TN, Nicovich PR, Oldre A, Park D, Parry S, Perkins J, Potekhina L, Reid D, Robertson M, Sandman D, Schroedter M, Slaughterbeck C, Soler-Llavina C, Sulc J, Szafer A, Tasic B, Taskin N, Teeter C, Thatra N, Tung H, Wakeman W, Williams G, Young R, Zhou Z, Farrell C, Peng H, Hawrylycz MJ, Lein E, Ng L, Arkhipov A, Bernard A, Phillips J, Zeng H, Koch C
Journal of Biomolecular Techniques
December 30, 2019
July 12, 2018
Daigle TL, Madisen L, Hage TA, Valley MT, Knoblich U, Larsen RS, Takeno MM, Huang L, Gu H, Larsen R, Mills M, Bosma-Moody A, Siverts LA, Walker M, Graybuck LT, Yao Z, Fong O, Nguyen TN, Garren E, Lenz GH, Chavarha M, Pendergraft J, Harrington J, Hirokawa KE, Harris JA, Nicovich PR, McGraw MJ, Ollerenshaw DR, Smith KA, Baker CA, Ting JT, Sunkin SM, Lecoq J, Lin MZ2, Boyden ES, Murphy GJ, da Costa NM, Waters J, Li L, Tasic B, Zeng H
November 16, 2018
Tasic B, Nicovich PR
November 1, 2018
Kalmbach BE, Buchin A, Long B, Close J, Nandi A, Miller JA, Bakken TE, Hodge RD, Chong P, de Frates R, Dai K, Maltzer Z, Nicovich PR, Keene CD, Silbergeld DL, Gwinn RP, Cobbs C, Ko AL, Ojemann JG, Koch C, Anastassiou CA, Lein ES, Ting JT
Nicovich PR, Owen DM, Gaus K
September 13, 2016
Pageon SV, Tabarin T, Yamamoto,Y, Ma Y, Bridgeman JS, Cohnen A, Benzing C, Gao Y, Crowther MD, Tungatt K
Biomedical Optics Express
April 1, 2016
Ma Y, Benda A, Nicovich PR, Gaus K
Molecular Biology of the Cell
November 7, 2016
Pageon SV, Nicovich PR, Mollazade M, Tabarin T, Gaus K
November 23, 2016
Nicovich PR, Janco M, Sobey T, Gajwani M, Obeidy P, Whan R, Gaus K, Gunning PW, Coster AC, Böcking T
Biosensors & Bioelectronics
October 24, 2016
Lu X, Nicovich PR, Gaus K, Gooding JJ