
Costas Anastassiou, Ph.D.
Assistant Investigator
Costas Anastassiou leads the translational neuroscience program at the Allen Institute, focusing on understanding brain disorders such as epilepsy and Alzheimer’s disease and developing novel therapies for these disoders (e.g. via neuroprosthetic interventions). Concurrently, Anastassiou’ team contributes to multiple other Institute programs.
After completing his undergraduate studies in chemical engineering at ETH Zurich, Anastassiou conducted his Ph.D. in the department of bioengineering at Imperial College London on CNS biosensing methodologies. He then joined Caltech as a postdoctoral fellow where he studied the origin and functionality of extracellular electric fields in brain circuits. Anastassiou has received a number of awards such as the SNSF early and advanced postodoctoral awards, the EPSRC LSI postdoctoral fellowship and the SNSF Professorship award.

Selected Publications View Publications
Classification of electrophysiological and morphological neuron types in mouse visual cortex
Nature Neuroscience
June 17, 2019
Gouwens NW, Sorensen SA, Berg J, Lee C, Jarsky T, Ting J, Sunkin S, Feng D, Anastassiou C, Barkan E, Bickley K, Blesie N, Braun T, Brouner K, Budzillo A, Caldejon S, Casper T, Castelli D, Chong P, Crichton K, Cuhaciyan C, Daigle T, Dalley R, Dee N, Desta T, Dingman S, Doperalski A, Dotson N, Egdorf T, Fisher M, de Frates RA, Garren E, Garwood M, Gary A, Gaudreault N, Godfrey K, Gorham M, Gu H, Habel C, Hadley K, Harrington J, Harris J, Henry A, Hill D, Josephsen S, Kebede S, Kim L, Kroll M, Lee B, Lemon T, Liu X, Long B, Mann R, McGraw M, Mihalas S, Mukora A, Murphy GJ, Ng L, Ngo K, Nguyen TN, Nicovich PR, Oldre A, Park D, Parry S, Perkins J, Potekhina L, Reid D, Robertson M, Sandman D, Schroedter M, Slaughterbeck C, Soler-Llavina C, Sulc J, Szafer A, Tasic B, Taskin N, Teeter C, Thatra N, Tung H, Wakeman W, Williams G, Young R, Zhou Z, Farrell C, Peng H, Hawrylycz MJ, Lein E, Ng L, Arkhipov A, Bernard A, Phillips J, Zeng H, Koch C
BioNet: A Python interface to NEURON for modeling large-scale networks
PLOS | ONE
August 2, 2018
Gratiy SL, Billeh YN, Dai K, Mitelut C, Feng D, Gouwens NW, Cain N, Koch C, Anastassiou CA, Arkhipov A
Neuron
November 1, 2018
Kalmbach BE, Buchin A, Long B, Close J, Nandi A, Miller JA, Bakken TE, Hodge RD, Chong P, de Frates R, Dai K, Maltzer Z, Nicovich PR, Keene CD, Silbergeld DL, Gwinn RP, Cobbs C, Ko AL, Ojemann JG, Koch C, Anastassiou CA, Lein ES, Ting JT
From Maxwell's equations to the theory of current-source density analysis
European Journal of Neuroscience
February 8, 2017
Gratiy SL, Halnes G, Denman D, Hawrylycz MJ, Koch C, Einevoll GT, Anastassiou CA
Fully integrated silicon probes for high-density recording of neural activity
Nature
November 8, 2017
Jun JJ, Steinmetz NA, Siegle JH, Denman DJ, Bauza M, Barbarits B, Lee AK, Anastassiou CA, Andrei A, Aydın Ç, Barbic M, Blanche TJ, Bonin V, Couto J, Dutta B, Gratiy SL, Gutnisky DA, Häusser M, Karsh B, Ledochowitsch P, Lopez CM, Mitelut C, Musa S, Okun M, Pachitariu M, Putzeys J, Rich PD, Rossant C, Sun WL, Svoboda K, Carandini M, Harris KD, Koch C5 O'Keefe J, Harris TD
Local Field Potentials Encode Place Cell Ensemble Activation during Hippocampal Sharp Wave Ripples
Neuron
August 5, 2015
Taxidis J, Anastassiou CA, Diba K, Koch C
Cell-type- and activity-dependent extracellular correlates of intracellular spiking
Journal of Neurophysiology
May 20, 2015
Anastassiou CA, Perin R, Buzsaki G, Markram H, Koch C
Theta Phase Segregation of Input-Specific Gamma Patterns in Entorhinal-Hippocampal Networks
Neuron
September 24, 2014
Schomburg EW, Fernández-Ruiz A, Mizuseki K, Berényi A, Anastassiou CA, Koch C, Buzsáki G
Neuron
July 24, 2013
Reimann MW, Anastassiou CA, Perin R, Hill SL, Markram H, Koch C
The origin of extracellular fields and currents — EEG, ECoG, LFP and spikes
Nature Reviews Neuroscience
May 18, 2012
Buzsáki G, Anastassiou CA, Koch C
Ephaptic coupling of cortical neurons
Nature Neuroscience
February 2011
Anastassiou CA, Perin R, Markram H, Koch C
Transcranial electric stimulation entrains cortical neuronal populations in rats
Journal of Neuroscience
August 2010
Ozen S, Sirota A, Belluscio MA, Anastassiou CA, Stark E, Koch C, Buzsáki G