Arnold Kriegstein, M.D., Ph.D.
University of California, San Francisco
Arnold Kriegstein is a member of the Institute of Medicine of the National Academies, and the John Bowes Distinguished Professor in Stem Cell and Tissue Biology and Founding Director of the Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research at the University of California, San Francisco. Dr. Kriegstein received his BA from Yale University and his MD and PhD degrees from New York University in 1977 where his thesis advisor was Dr. Eric Kandel. He subsequently completed Residency training in Neurology at the Brigham and Women’s Hospital, Children’s Hospital, and Beth Israel Hospital in Boston and is a board licensed neurologist. He has held academic appointments at Stanford University, Yale University, and Columbia University. In 2001 he was named the John and Elizabeth Harris Professor of Neurology and became the founding Director of the Neural Stem Cell Program at Columbia University. In 2004 he moved to UCSF. Dr. Kriegstein’s research focuses on the way in which neural stem and progenitor cells produce neurons in the embryonic brain. His lab found that radial glial cells, long thought to simply guide nerve cells during migration, are neuronal stem cells in the developing brain. He also described a class of intermediate precursor cells produced by radial glia, suggesting a new mechanism for the generation of cell diversity. Recently, he has focused on the developing human brain and identified a radial glia-like progenitor cell in the outer subventricular zone that contributes to the huge expansion of neuron number that characterizes human cerebral cortex.