Abhi Aggarwal
Research Associate II
abhi.aggarwal@alleninstitute.org
Abhi is in the Optophysiology program at the Allen Institute for Neural Dynamics. His research is focused on developing biosensors and tools for neural imaging in vivo. He received a BSc in Biology and Chemistry from University of Alberta, Alberta, Canada. He later joined Kaspar Podgorski’s lab at HHMI Janelia Research Campus where he developed genetically encoded neurotransmitter indicators for recording synaptic activity. Abhi joined the Allen Institute in Jan 2022, where he is working to engineer novel tools to help scientists study computations that occur in individual neurons in the brain.
Selected Publications
bioRxiv
February 2022
Aggarwal A, Liu R, Chen Y, Ralowicz AJ, Bergerson SJ, Tomaska F, Hanson TL, Hasseman JP, Reep D, Tsegaye G, Yao P, Ji X, Kloos M, Walpita D, Patel R, Tilberg PW, Mohar B, Looger L, Marvin J, Hoppa M, Konnerth A, Kleinfeld D, Schreiter ER, Podgorski K
A genetically encoded fluorescent biosensor for extracellular L-lactate
Nature Communications
December 2021
Nasu Y, Murphy-Royal C, Wen Y, Haidey JN, Molina RS, Aggarwal A, Zhang S, Kamijo Y, Paque Mt, Podgorski K, Drobizhev M, Bains JS, Lemieux MJ, Gordon GR, Campbell RE
ACS Sensors
June 2020
Zarowny L, Aggarwal A, Rutten VMS, Kolb I, The GENIE Project, Patel R, Huang H, Chang Y, Phan T, Kanyo R, Ahrens MB, Allison WT, Podgorski K, Campbell RE
jYCaMP: an optimized calcium indicator for two-photon imaging at fiber laser wavelengths
Nature Methods
May 25, 2020
Mohr MA, Bushey D, Aggarwal A, Marvin JS, Kim JJ, Marquez EJ, Liang Y, Patel R, Macklin JJ, Lee C, Tsang A, Tsegaye G, Ahrens AM, Chen JL, Kim DS, Wong AM, Looger LL, Schreiter ER, Podgorski K
Far-red fluorescent genetically encoded calcium ion indicators
bioRxiv
2020
Dalangin R, Drobizhev M, Molina RS, Aggarwal A, Patel R, Abdelfattah AS, Zhao Y, Wu J, Podgorski K, chreiter ER, Hughes TE, Campbell RE, Shen Y
Genetically encoded fluorescent indicators for imaging intracellular potassium ion concentration
Communications Biology
January 2019
Shen Y, Wu S, Rancic V, Aggarwal A, Qian Y, Miyashita S, Ballanyi K, Campbell RE, Dong M